2763  charam  khaw-ram'

 a primitive root; to 
seclude; specifically (by a 
ban) to devote to religious 
uses (especially 
destruction); physical and 
reflexive, to be blunt as to 
the nose:--make accursed, 
consecrate, (utterly) 
destroy, devote, forfeit, 
have a flat nose, utterly 
(slay, make away).