John Gill's Bible Commentary Ver. 6. For which things' sake , etc.] Those sins above mentioned, ( Colossians 3:5): the wrath of God ; the effects of it in temporal judgments, and eternal ruin and destruction, the wrath to come, which all are deserving of, and there is only deliverance from by Christ: cometh upon the children of disobedience : who are disobedient both to the law of God, and Gospel of Christ: who are unbelievers in him, are rebellious and gainsaying, reject his calls, the persuasions of his ministers, set at nought his counsel, and will have none of his reproof. There have been already instances of God's displeasure at sin, his indignation against it, and his judgments on account of it: his wrath is revealed from heaven, and it will come down from thence on disobedient and rebellious sinners, and that suddenly, and with great power, like a mighty torrent, that there will be no standing before it. This is a reason why such who have life in Christ should mortify, repress, and abstain from the above sins; for though this regards sinners, and ungodly persons, yet the effects of God's wrath on such show how much such sins are displeasing to him, and detested by him, and therefore to be avoided by the saints.
Matthew Henry Commentary
Verses 5-11 - It is our duty to mortify our members which incline to the things of the world. Mortify them, kill them, suppress them, as weeds or vermi which spread and destroy all about them. Continual opposition must be made to all corrupt workings, and no provision made for carna indulgences. Occasions of sin must be avoided: the lusts of the flesh and the love of the world; and covetousness, which is idolatry; love of present good, and of outward enjoyments. It is necessary to mortif sins, because if we do not kill them, they will kill us. The gospe changes the higher as well as the lower powers of the soul, an supports the rule of right reason and conscience, over appetite an passion. There is now no difference from country, or conditions an circumstances of life. It is the duty of every one to be holy, becaus Christ is a Christian's All, his only Lord and Saviour, and all his hope and happiness.
Greek Textus Receptus
δι 1223 PREP α 3739 R-APN ερχεται 2064 5736 V-PNI-3S η 3588 T-NSF οργη 3709 N-NSF του 3588 T-GSM θεου 2316 N-GSM επι 1909 PREP τους 3588 T-APM υιους 5207 N-APM της 3588 T-GSF απειθειας 543 N-GSF
Vincent's NT Word Studies
6. Wrath - cometh. Compare Rom. i. 18. The present tense denotes the certainty of the future event, as Matt. xvii. 11; John iv. 21. The best texts omit upon the children of disobedience.
Robertson's NT Word Studies
3:6 {Cometh the wrath of God} (ercetai he orge tou qeou). Paul does not regard these sins of the flesh as matters of indifference, far otherwise. Many old MSS. do not have "upon the sons of disobedience," genuine words in #Eph 5:6.