John Gill's Bible Commentary Ver. 1. When the Lord thy God hath cut off the nations whose land the Lord thy God giveth thee , etc.] The seven nations of the land of Canaan, whose destruction was of the Lord for their sins, and whose land was a gift of him that had a right to dispose of it to the children of Israel; (see Deuteronomy 12:29) and thou succeedest them, and dwellest in their cities, and in their houses ; should possess their land in their stead, by virtue of the gift of it to them by the Lord, and inhabit their cities and houses built by them.
Matthew Henry Commentary
Verses 1-13 - Here is the law settled between the blood of the murdered, and the blood of the murderer; provision is made, that the cities of refug should be a protection, so that a man should not die for that as crime, which was not his willing act. In Christ, the Lord ou Righteousness, refuge is provided for those who by faith flee unto him But there is no refuge in Jesus Christ for presumptuous sinners, who go on still in their trespasses. Those who flee to Christ from their sins shall be safe in him, but not those who expect to be sheltered by his in their sins.
Original Hebrew כי3588 יכרית3772 יהוה3068 אלהיך430 את853 הגוים1471 אשׁר834 יהוה3068 אלהיך430 נתן5414 לך את853 ארצם776 וירשׁתם3423 וישׁבת3427 בעריהם5892 ובבתיהם׃1004